Article
Expression analysis of the human adducin gene family and evidence of ADD2 beta4 multiple splicing variants.
Biochemical and biophysical research communications - 19 Sept 2003
Citterio Lorena, Tizzoni Laura, Catalano Marco, Zerbini Gianpaolo, Bianchi Giuseppe, Barlassina Cristina
Abstract excerpt
Adducin is a cytoskeleton heterodimeric protein. Its subunits are encoded by three related genes (ADD1, ADD2, and ADD3) which show alternative spliced variants. Adducin polymorphisms are involved in blood pressure regulation in humans and rats. We have analyzed mRNA distribution of ADD gene family in human tissues and cells with Real-Time TaqMan RT-PCR. Whereas ADD1 is ubiquitously distributed, ADD3 is more...
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