Article
Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1997
Lisovoski F, Akli S, Peltekian E, Vigne E, Haase G, Perricaudet M, Dreyfus P A, Kahn A, Peschanski M
Abstract excerpt
Synthesis of the ciliary neurotrophic factor (CNTF) and its specific receptor (CNTFRalpha) is widespread in the intact CNS, but potential biological roles for this system remain elusive. Contradictory results have been obtained concerning a possible effect on the morphological and biochemical phe...
Topics
- Adenoviridae
- Animals
- Astrocytes
- Brain
- Cell Differentiation
- Ciliary Neurotrophic Factor
- Gene Transfer Techniques
- Genetic Vectors
- Injections
- Nerve Tissue Proteins
- Phenotype