Article
Tick-Borne Encephalitis Virus Infects Rat Astrocytes but Does Not Affect Their Viability
20 Jan 2014
Abstract excerpt
Tick-borne encephalitis virus (TBEV) causes one of the most dangerous human neuroinfections in Europe and Asia. To infect neurons it must cross the blood-brain-barrier (BBB), and presumably also cells adjacent to the BBB, such as astrocytes, the most abundant glial cell type. However, the knowledge about the viral infection of glial cells is fragmental. Here we studied whether TBEV infects rat astrocytes. Rats...
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