CNTF induces GFAP in a S-100 alpha brain cell population: the pattern of CNTF-alpha R suggests an indirect mode of action.

doi:10.1016/s0165-3806(96)00180-0

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Article

CNTF induces GFAP in a S-100 alpha brain cell population: the pattern of CNTF-alpha R suggests an indirect mode of action.

Brain research. Developmental brain research - 20 Feb 1997

Kahn M A, Ellison J A, Chang R P, Speight G J, de Vellis J

Abstract excerpt

In a recent report, we demonstrated that intracerebral injections of the pleiotropic cytokine, ciliary neurotrophic factor (CNTF), into developing postnatal rats evoked a severe inflammatory response as determined by the appearance of reactive astrocytes and activated microglia. Considering the l...

Topics

Animals
Astrocytes
Biomarkers
Brain
Ciliary Neurotrophic Factor
Female
Gene Expression Regulation
Glial Fibrillary Acidic Protein
Male
Microglia
Nerve Growth Factors
Nerve Tissue Proteins
Phenotype
Rats
Rats, Wistar
Receptor, Ciliary Neurotrophic Factor
Receptors, Nerve Growth Factor
Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 9051264
DOI: 10.1016/s0165-3806(96)00180-0

Genes

CNTF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9051264-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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