Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CNTF induces GFAP in a S-100 alpha brain cell population: the pattern of CNTF-alpha R suggests an indirect mode of action.

Brain research. Developmental brain research - 20 Feb 1997

Kahn M A, Ellison J A, Chang R P, Speight G J, de Vellis J

Abstract excerpt

In a recent report, we demonstrated that intracerebral injections of the pleiotropic cytokine, ciliary neurotrophic factor (CNTF), into developing postnatal rats evoked a severe inflammatory response as determined by the appearance of reactive astrocytes and activated microglia. Considering the likely involvement of CNTF in the injury response, we felt it was important to further understand the role of CNTF in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Brain
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Phenotype

Share to Rats, Wistar

Share to Recombinant Proteins

Source

Identifiers

PMID: 9051264
DOI: 10.1016/s0165-3806(96)00180-0

Genes

CNTF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CNTF induces GFAP in a S-100 alpha brain cell population: the pattern of CNTF-alpha R suggests an indirect mode of action.PMID 9051264Read ↗

Glial fibrillary acidic protein gene promoter is differently modulated by transforming growth factor‐beta 1 in astrocytes from distinct brain regionsSemantic proximity Read ↗

Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer.Semantic proximity Read ↗

kappa-opioid receptor expression defines a phenotypically distinct subpopulation of astroglia: relationship to Ca2+ mobilization, development, and the antiproliferative effect of opioids.Semantic proximity Read ↗

Cell growth suppression of astrocytoma C6 cells by glial fibrillary acidic protein cDNA transfection.Semantic proximity Read ↗

Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes.Semantic proximity Read ↗

TGF-alpha induces a stationary, radial-glia like phenotype in cultured astrocytes.Semantic proximity Read ↗

Bone Morphogenetic Proteins Induce Differentiation in Astrocyte Lineage CellsSemantic proximity Read ↗

Insulin influences astroglial morphology and glial fibrillary acidic protein (GFAP) expression in organotypic cultures.Semantic proximity Read ↗

Transforming growth factor beta1 may directly influence gonadotropin-releasing hormone gene expression in the rat hypothalamus.Semantic proximity Read ↗

CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro.Semantic proximity Read ↗

GDNF induces the calretinin phenotype in cultures of embryonic striatal neurons.Semantic proximity Read ↗

Insulin‐like growth factor‐I increases astrocyte intercellular gap junctional communication and connexin43 expression in vitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.