Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transforming growth factor alpha expression as a response of murine motor neurons to axonal injury and mutation-induced degeneration.

Journal of neuropathology and experimental neurology - 1 May 1997

Lisovoski F, Blot S, Lacombe C, Bellier J P, Dreyfus P A, Junier M P

Abstract excerpt

We previously showed that degenerating adult motor neurons of the murine mutant wobbler, a model of spinal muscular atrophy, express Transforming Growth Factor alpha (TGF alpha), a growth factor endowed with glio- and neurotrophic activities. Here, we evaluated whether TGF alpha expression is a general response of adult motor neurons to injury. Synthesis of its precursor (pro-TGF alpha) was investigated in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Mice
Share to Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Muscles

Share to Mutation

Share to Protein Precursors

Share to RNA, Messenger

Source

Identifiers

PMID: 9143258
DOI: 10.1097/00005072-199705000-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transforming growth factor alpha expression as a response of murine motor neurons to axonal injury and mutation-induced degeneration.PMID 9143258Read ↗

Transforming Growth Factor-&#946; Signaling in Motor Neuron DiseasesSemantic proximity Read ↗

Up-regulation of glial cell line-derived neurotrophic factor (GDNF) expression in regenerating muscle fibers in neuromuscular diseasesSemantic proximity Read ↗

Glial TGFβ activity promotes axon survival in peripheral nervesSemantic proximity Read ↗

The transforming growth factor-betas: multifaceted regulators of the development and maintenance of skeletal muscles, motoneurons and Schwann cells.Semantic proximity Read ↗

Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axisSemantic proximity Read ↗

GDNF gene delivery to injured adult CNS motor neurons promotes axonal growth, expression of the trophic neuropeptide CGRP, and cellular protection.Semantic proximity Read ↗

The Neuregulin1/ErbB system is selectively regulated during peripheral nerve degeneration and regenerationSemantic proximity Read ↗

Transforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injury.Semantic proximity Read ↗

Assessment of the Role of NOGO Gene Block in Enhancing the Neuro-regenerative Effect of Mesenchymal Stem Cells.Semantic proximity Read ↗

TGF-β and the regulation of neuron survival and deathSemantic proximity Read ↗

Tumor necrosis factor-α gene transfer induces cachexia and inhibits muscle regenerationSemantic proximity Read ↗

Muscular dystrophy in adult and aged anti-NGF transgenic mice resembles an inclusion body myopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.