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Article

Preferential mutagenesis of lacZ integrated at unique sites in the Escherichia coli chromosome.

Molecular & general genetics : MGG - 1 Aug 1997

Liu S K, Tseng J N, Shiuan D, Hanawalt P C

Abstract excerpt

To study the variation in spontaneous mutation frequencies in different chromosomal domains, a mini-Mu-kan-lacZ- transposable element was constructed to insert the lacZ-(Trp570 --> Opal) allele into many different loci in the Escherichia coli chromosome. Papillation on MacConkey lactose plates wa...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Chromosomes, Bacterial
DNA Primers
DNA Transposable Elements
DNA, Bacterial
Escherichia coli
Genetic Linkage
Kanamycin Resistance
Lac Operon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutagenesis, Insertional

Polymerase Chain Reaction

Source

Identifiers

PMID: 9294029
DOI: 10.1007/s004380050517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9294029-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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