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Article

p53 and cyclin D1 as prognostic factors in squamous cell carcinoma of the larynx.

The Laryngoscope - 1 Jan 2003

Vielba Raquel, Bilbao Juan, Ispizua Angel, Zabalza Iñaki, Alfaro Jesús, Rezola Ricardo, Moreno Enrique, Elorriaga Jon, Alonso Ibón, Baroja Antonio, de la Hoz Carmen

Abstract excerpt

OBJECTIVES/HYPOTHESIS: Proteins p53 and cyclin D1 play a crucial role in cell cycle control. Protein p53 mutations are one of the most common genetic alterations in human cancer, and cyclin D1 gene amplification has been found to be associated with poor prognosis in different types of tumors. Functional alterations of these proteins may play an important role both in the carcinogenesis of squamous carcinomas of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12514403
DOI: 10.1097/00005537-200301000-00031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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