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Article

Association of a group I intron with its splice junction in 50S ribosomes: implications for intron toxicity.

RNA (New York, N.Y.) - 1 Sept 1997

Nikolcheva T, Woodson S A

Abstract excerpt

The effect of genetic context on splicing of group I introns is not well understood at present. The influence of ribosomal RNA conformation on splicing of rDNA introns in vivo was investigated using a heterologous system in which the Tetrahymena group I intron is inserted into the homologous position of the Escherichia coli 23S rRNA. Mutations that block splicing in E. coli result in accumulation of unspliced 23S...

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Identifiers

PMID: 9292500
PMCID: PMC1369547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a group I intron with its splice junction in 50S ribosomes: implications for intron toxicity.PMID 9292500Read ↗

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Facilitation of group I splicing in vivo: misfolding of the Tetrahymena IVS and the role of ribosomal RNA exons.Semantic proximity Read ↗

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