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Article

Mutator phenotype in Msh2-deficient murine embryonic fibroblasts.

Cancer research - 1 Sept 1997

Reitmair A H, Risley R, Bristow R G, Wilson T, Ganesh A, Jang A, Peacock J, Benchimol S, Hill R P, Mak T W, Fishel R, Meuth M

Abstract excerpt

Embryonic fibroblast cell lines were established from mice deficient, heterozygous, or proficient for Msh2, one of the three known DNA mismatch repair genes involved in hereditary nonpolyposis colon cancer (HNPCC). Cell lines were established by transfection of primary mouse embryo fibroblasts with E7 and Ras oncogenes or mutant p53. Spontaneously immortalized cells derived from the primary cultures were also...

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Identifiers

PMID: 9288785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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