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Article

Mechanisms underlying mismatch repair deficiencies in normal cells.

Genes, chromosomes & cancer - 1 Nov 1997

Moliaka Y K, Cella M, Chudina A P, Kolesnikova T N, Terracciano L, Cathomas G, Bochkov N P, Buerstedde J M

Abstract excerpt

Hereditary nonpolyposis colon cancer (HNPCC) is an autosomal dominantly inherited cancer predisposition which is linked to heterozygous mutations in mismatch repair genes. HNPCC tumour cells, in which the remaining wild-type copy of the mismatch repair gene is inactivated, display instability of microsatellite markers reflecting a defect in mismatch repair. Recently, patients carrying either one of two distinct...

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Source

Identifiers

PMID: 9365839

Genes

MLH1
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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