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Article

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle.

Nature genetics - 1 Sept 1997

Grobet L, Martin L J, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Ménissier F, Massabanda J, Fries R, Hanset R, Georges M

Abstract excerpt

An exceptional muscle development commonly referred to as 'double-muscled' (Fig. 1) has been seen in several cattle breeds and has attracted considerable attention from beef producers. Double-muscled animals are characterized by an increase in muscle mass of about 20%, due to general skeletal-muscle hyperplasia-that is, an increase in the number of muscle fibers rather than in their individual diameter. Although...

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PMID: 9288100
DOI: 10.1038/ng0997-71

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