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Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1998

Grobet L, Poncelet D, Royo L J, Brouwers B, Pirottin D, Michaux C, Ménissier F, Zanotti M, Dunner S, Georges M

Abstract excerpt

We have determined the entire myostatin coding sequence for 32 double-muscled cattle sampled from ten European cattle breeds. Seven DNA sequence polymorphisms were identified, of which five would be predicted to disrupt the function of the protein, one is a conservative amino acid substitution, a...

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Mutation
Alleles
Haplotypes
Cattle
Muscle, Skeletal
Transforming Growth Factor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9501304
DOI: 10.1007/s003359900727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9501304-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle.PMID 9501304Read ↗

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