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Article

Functional effect of mir-27b on myostatin expression: a relationship in Piedmontese cattle with double-muscled phenotype.

BMC genomics - 19 Mar 2013

Miretti Silvia, Martignani Eugenio, Accornero Paolo, Baratta Mario

Abstract excerpt

BACKGROUND: In Piedmontese cattle the double-muscled phenotype is an inherited condition associated to a point mutation in the myostatin (MSTN) gene. The Piedmontese MSTN missense mutation G938A is translated to C313Y myostatin protein. This mutation alters MSTN function as a negative regulator of muscle growth, thereby inducing muscle hypertrophy. MiRNAs could play a role in skeletal muscle hypertrophy...

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Source

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Identifiers

PMID: 23510267
DOI: 10.1186/1471-2164-14-194
PMCID: PMC3605361

Genes

MSTN
IGF1
TEAD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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