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Article

The myostatin gene: an overview of mechanisms of action and its relevance to livestock animals.

Animal genetics - 1 Dec 2018

Aiello D, Patel K, Lasagna E

Abstract excerpt

Myostatin, also known as growth differentiation factor 8, a member of the transforming growth factor-beta super-family, is a negative regulator of muscle development. Myostatin acts at key points during pre- and post-natal life of amniotes that ultimately determine the overall muscle mass of an animal. Mutations have already demonstrated the impact of attenuating myostatin activity on muscle development. A number...

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PMID: 30125951
DOI: 10.1111/age.12696

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