Article
Structure of the Trypanosoma brucei U6 snRNA gene promoter.
Molecular and biochemical parasitology - 1 Sept 1997
Nakaar V, Günzl A, Ullu E, Tschudi C
Abstract excerpt
Transcription in vivo of small nuclear and cytoplasmic RNA genes of Trypanosoma brucei was previously shown to require the A and B blocks of a divergently transcribed tRNA or tRNA-like gene located approximately 100 nucleotides (nt) upstream. To understand the functioning of these transcription units, we have used the U6 snRNA/tRNA(Thr) genes as a model system. Saturation mutagenesis revealed that for...
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