Article
TFIIIC-independent in vitro transcription of yeast tRNA genes.
Journal of molecular biology - 9 Jun 2000
Dieci G, Percudani R, Giuliodori S, Bottarelli L, Ottonello S
Abstract excerpt
The most peculiar transcriptional property of eukaryotic tRNA genes, as well as of other genes served by RNA polymerase III, is their complete dependence on the intragenic interaction platform provided by transcription factor IIIC (TFIIIC) for the productive assembly of the TBP-containing initiation factor TFIIIB. The sole exception, in yeast, is the U6 RNA gene, which is able to exploit a TATAAATA element, 30 bp...
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