Transcription of the Trypanosoma brucei spliced leader RNA gene is dependent only on the presence of upstream regulatory elements.

doi:10.1016/s0166-6851(96)02816-2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Transcription of the Trypanosoma brucei spliced leader RNA gene is dependent only on the presence of upstream regulatory elements.

Molecular and biochemical parasitology - 1 Mar 1997

Günzl A, Ullu E, Dörner M, Fragoso S P, Hoffmann K F, Milner J D, Morita Y, Nguu E K, Vanacova S, Wünsch S, Dare A O, Kwon H, Tschudi C

Abstract excerpt

The spliced leader (SL) RNA plays a key role in mRNA maturation in trypanosomatid protozoa by providing the SL sequence, which is joined to the 5' end of every mRNA. As a first step towards a better understanding of the biogenesis and function of the SL RNA, we expressed a tagged SL RNA gene in a...

Topics

Amanitins
Animals
Base Sequence
Dicarboxylic Acids
Genes, Protozoan
Molecular Sequence Data
Mutation
Nucleic Acid Synthesis Inhibitors
Organophosphorus Compounds
Promoter Regions, Genetic
RNA Splicing
RNA, Messenger
RNA, Protozoan

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Trypanosoma brucei brucei

Source

Open in PubMed

Identifiers

PMID: 9108549
DOI: 10.1016/s0166-6851(96)02816-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9108549-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.