Article
Saturation mutagenesis of the Drosophila tRNA(Arg) gene B-Box intragenic promoter element: requirements for transcription activation and stable complex formation.
Nucleic acids research - 25 Mar 1990
Gaëta B A, Sharp S J, Stewart T S
Abstract excerpt
Transcription of eukaryotic tRNA genes is dependent on the A- and B-Box internal control regions (ICRs) and the upstream transcription modulatory region. The B-Box ICR spans nucleotides 52 to 62 and directs the primary binding of transcription factor C as the first step in the formation of a tran...
Topics
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- Drosophila melanogaster
- Genes
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Promoter Regions, Genetic
- RNA, Transfer, Amino Acid-Specific
- RNA, Transfer, Arg
- Templates, Genetic
- Transcription, Genetic