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Article

Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis.

Molecular and cellular biology - 1 Sept 1997

Larsson N, Marklund U, Gradin H M, Brattsand G, Gullberg M

Abstract excerpt

Oncoprotein 18 (Op18; also termed p19, 19K, metablastin, stathmin, and prosolin) is a conserved protein that regulates microtubule (MT) dynamics. Op18 is multisite phosphorylated on four Ser residues during mitosis; two of these Ser residues, Ser-25 and Ser-38, are targets for cyclin-dependent protein kinases (CDKs), and the other two Ser residues, Ser-16 and Ser-63, are targets for an unidentified protein...

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Identifiers

PMID: 9271428
DOI: 10.1128/MCB.17.9.5530
PMCID: PMC232401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis.PMID 9271428Read ↗

Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics.Semantic proximity Read ↗

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Aneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells.Semantic proximity Read ↗

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