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Article

Differential effect of two stathmin/Op18 phosphorylation mutants on Xenopus embryo development.

The Journal of biological chemistry - 22 Jun 2001

Küntziger T, Gavet O, Sobel A, Bornens M

Abstract excerpt

Stathmin/Op18 destabilizes microtubules in vitro and regulates microtubule polymerization in vivo. Both a microtubule catastrophe-promoting activity and a tubulin sequestering activity were demonstrated for stathmin in vitro, and both could contribute to microtubule depolymerization in vivo. Stathmin activity can be turned down by extensive phosphorylation on its four phosphorylatable serines, and down-regulation...

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Identifiers

PMID: 11297553
DOI: 10.1074/jbc.M101466200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential effect of two stathmin/Op18 phosphorylation mutants on Xenopus embryo development.PMID 11297553Read ↗

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