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Article

Distinct effects of various p53 mutants on differentiation and viability of human K562 leukemia cells.

Oncology research - 1 Jan 1997

Kremenetskaya O S, Logacheva N P, Baryshnikov A Y, Chumakov P M, Kopnin B P

Abstract excerpt

Mutations of the p53 tumor suppressor are often observed in various human tumors, including blast crisis of chronic myelogenous leukemia (CML). The pattern of p53 mutations in CML shows some peculiarities compared with majority of other malignancies. In particular, the substitutions at codon 273, one of the most common p53 alterations in various tumors, are not characteristic of CML. To test whether the...

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PMID: 9268986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Distinct effects of various p53 mutants on differentiation and viability of human K562 leukemia cells.PMID 9268986Read ↗

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