Article
In situ activation pattern of Drosophila EGF receptor pathway during development.
Science (New York, N.Y.) - 22 Aug 1997
Gabay L, Seger R, Shilo B Z
Abstract excerpt
Signaling cascades triggered by receptor tyrosine kinases (RTKs) participate in diverse developmental processes. The active state of these signaling pathways was monitored by examination of the in situ distribution of the active, dual phosphorylated form of mitogen-activated protein kinase (ERK) with a specific monoclonal antibody. Detection of the active state of the Drosophila epidermal growth factor receptor...
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