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Article

Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila.

Developmental biology - 1 Jan 1999

Lesokhin A M, Yu S Y, Katz J, Baker N E

Abstract excerpt

Dominant Ellipse mutant alleles of the Drosophila EGF receptor homologue (DER) dramatically suppress ommatidium development in the eye and induce ectopic vein development in the wing. Their phenotype suggests a possible role for DER in specifying the founder R8 photoreceptor cells for each ommatidium. Here we analyze the basis of Ellipse mutations and use them to probe the role of DER in eye development. We show...

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Source

Identifiers

PMID: 9882502
DOI: 10.1006/dbio.1998.9121

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila.PMID 9882502Read ↗

Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs.Semantic proximity Read ↗

Localization of DER and the pattern of cell divisions in wild-type and Ellipse eye imaginal discs.Semantic proximity Read ↗

Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation.Semantic proximity Read ↗

Developmental control by the Drosophila EGF receptor homolog DER.Semantic proximity Read ↗

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The Conserved MAPK Site in E(spl)-M8, an Effector of Drosophila Notch Signaling, Controls Repressor Activity during Eye Development.Semantic proximity Read ↗

The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway.Semantic proximity Read ↗

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