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Article

Studying Nonproliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Reed Bruce, Harden Nicholas

Abstract excerpt

For several decades, genetic analysis in Drosophila has made important contributions to the understanding of signaling by Egfr. Egfr has been well characterized with regard to its oncogenic potential but is also being studied for its roles in organismal development. We have recently developed dorsal closure of the Drosophila embryo as a system for characterizing Egfr regulation of events that do not involve...

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PMID: 28791646
DOI: 10.1007/978-1-4939-7219-7_16

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