Article
Poliovirus Sabin type 1 neutralization epitopes recognized by immunoglobulin A monoclonal antibodies.
Journal of virology - 1 Sept 1997
Fiore L, Ridolfi B, Genovese D, Buttinelli G, Lucioli S, Lahm A, Ruggeri F M
Abstract excerpt
Immunity to poliomyelitis is largely dependent on humoral neutralizing antibodies, both after natural (wild virus or vaccine) infection and after inactivated poliovirus vaccine inoculation. Although the production of local secretory immunoglobulin A (IgA) antibody in the gut mucosa may play a maj...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antibody Specificity
- Antigens, Viral
- Capsid
- Epitopes, B-Lymphocyte
- Female
- Humans
- Immunoglobulin A
- Mice
- Mice, Inbred BALB C
