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Article

Poliovirus Sabin type 1 neutralization epitopes recognized by immunoglobulin A monoclonal antibodies.

Journal of virology - 1 Sept 1997

Fiore L, Ridolfi B, Genovese D, Buttinelli G, Lucioli S, Lahm A, Ruggeri F M

Abstract excerpt

Immunity to poliomyelitis is largely dependent on humoral neutralizing antibodies, both after natural (wild virus or vaccine) infection and after inactivated poliovirus vaccine inoculation. Although the production of local secretory immunoglobulin A (IgA) antibody in the gut mucosa may play a major role in protection, most of information about the antigenic determinants involved in neutralization of polioviruses...

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Identifiers

PMID: 9261417
DOI: 10.1128/JVI.71.9.6905-6912.1997
PMCID: PMC191973

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Source receipt: pubmed, retrieved 7 Sept 2026.

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