Antigenic sites of poliovirus type 3 eliciting IgA monoclonal antibodies in orally immunized mice.

doi:10.1006/viro.2000.0786

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Article

Antigenic sites of poliovirus type 3 eliciting IgA monoclonal antibodies in orally immunized mice.

Virology - 15 Mar 2001

Buttinelli G, Ruggeri F M, Marturano J, Novello F, Donati V, Fiore L

Abstract excerpt

A panel of neutralizing IgA monoclonal antibodies was produced from mice orally inoculated with poliovirus type 3 Sabin and cholera toxin as adjuvant. Low levels of neutralizing antibodies were elicited in mice after several boosts, but only in the presence of cholera toxin. Characterization of IgA MAbs by neutralization-escape virus mutants showed that all but one neutralizing MAbs against type 3 poliovirus were...

Topics

Adjuvants, Immunologic
Animals
Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Binding Sites, Antibody
Capsid
Cholera Toxin
Epitopes
Female
Immunoglobulin A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred BALB C

Molecular Sequence Data

Mutation

Neutralization Tests

Poliovirus

Poliovirus Vaccine, Oral

Source

Open in PubMed

Identifiers

PMID: 11277698
DOI: 10.1006/viro.2000.0786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11277698-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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