Analysis of human T cell and B cell responses against U small nuclear ribonucleoprotein 70-kd, B, and D polypeptides among patients with systemic lupus erythematosus and mixed connective tissue disease.

doi:10.1002/art.1780400818

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Article

Analysis of human T cell and B cell responses against U small nuclear ribonucleoprotein 70-kd, B, and D polypeptides among patients with systemic lupus erythematosus and mixed connective tissue disease.

Arthritis and rheumatism - 1 Aug 1997

Holyst M M, Hill D L, Hoch S O, Hoffman R W

Abstract excerpt

OBJECTIVE: To analyze T and B cell reactivity with U small nuclear RNP (snRNP) 70-kd, B, and D polypeptides among patients with connective tissue disease (CTD) and to examine the functional characteristics of snRNP-reactive T cell clones. METHODS: We used an snRNP enzyme-linked immunosorbent assa...

Topics

Adult
Antibody Formation
Autoantibodies
B-Lymphocytes
Clone Cells
Cytokines
Cytotoxicity, Immunologic
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoblotting
Lupus Erythematosus, Systemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mixed Connective Tissue Disease

Peptides

Phenotype

RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 9259431
DOI: 10.1002/art.1780400818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9259431-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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