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Mixed connective tissue disease

1 Sept 2000

Abstract excerpt

A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in murine models of disease. Hypotheses implicating modified self-antigens and/or infectious agents in the...

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Identifiers

PMID: 10990174
DOI: 10.1097/00002281-200009000-00006

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Source receipt: pubmed, retrieved 7 Sept 2026.

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