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Article

Epitope patterns of anti-RNP antibodies in rheumatic diseases. Evidence for an antigen-driven autoimmune response.

Arthritis and rheumatism - 1 Jun 1990

Habets W J, Hoet M H, van Venrooij W J

Abstract excerpt

Autoantibodies against small nuclear ribonucleoproteins (snRNP) are common in systemic lupus erythematosus and related disorders. The 3 categories, anti-(U1)RNP, anti-(U1, U2)RNP, and anti-Sm, all contain a common antibody specificity directed against the U1 snRNP-associated A protein. To determine the specificity of anti-U1 snRNP A protein antibodies for various antigenic sites, we tested 26 different...

Topics

Antibodies, Antinuclear
Autoantigens
Autoimmunity
Chromosome Deletion
Epitopes
Humans
Immune Sera
Mutation
Rheumatic Diseases
Ribonucleoproteins
Ribonucleoproteins, Small Nuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1694665
DOI: 10.1002/art.1780330610

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1694665-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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