Article
Major histocompatibility complex class II gene associations with anti-U1 small nuclear ribonucleoprotein antibody. Relationship to immunoreactivity with individual constituent proteins.
Arthritis and rheumatism - 1 Mar 1995
Kuwana M, Okano Y, Kaburaki J, Tsuji K, Inoko H
Abstract excerpt
OBJECTIVE: To better define immunogenetic associations with the anti-U1 ribonucleoprotein (U1 RNP) autoantibody response. METHODS: HLA class II alleles were determined by genotyping in 49 Japanese rheumatic disease patients with anti-U1 RNP antibody and 43 race-matched healthy controls. Immunorea...
Topics
- Amino Acid Sequence
- Autoantibodies
- Case-Control Studies
- Epitopes
- Gene Frequency
- Genes, MHC Class II
- Genetic Linkage
- Genotype
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Immunoblotting
- Molecular Sequence Data
- Odds Ratio
- Rheumatic Diseases
- Ribonucleoprotein, U1 Small Nuclear