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Article

Autoimmune response to the spliceosome

1 Jun 1995

Abstract excerpt

OBJECTIVE: To assess the significance of autoantibodies to RA33, the A2 protein of the heterogeneous nuclear ribonucleoproteins (hnRNP), and to the related hnRNP proteins A1, B1, and B2 in rheumatic diseases. METHODS: Using a partially purified preparation of hnRNP-A and hnRNP-B proteins, sera from 303 patients with various rheumatic diseases were investigated by immunoblotting. For the analysis of...

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Identifiers

PMID: 7779120
DOI: 10.1002/art.1780380610

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