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Article

U1—70‐kd autoantibody–positive mixed connective tissue disease in children. A longitudinal clinical and serologic analysis

1 Nov 1993

Abstract excerpt

OBJECTIVE: To obtain longitudinal data on the clinical, serologic, and immunogenetic features of children with mixed connective tissue disease (MCTD). METHODS: Eleven children with MCTD were followed up for a mean of 9.8 years. Enzyme-linked immunosorbent assay and immunoblotting were used to analyze sera for autoantibodies to small nuclear ribonucleoprotein polypeptides. HLA types were determined in 9 patients,...

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PMID: 8240436
DOI: 10.1002/art.1780361115

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