Article
Transvection in the Drosophila Abd-B domain: extensive upstream sequences are involved in anchoring distant cis-regulatory regions to the promoter.
Genetics - 1 Jun 1998
Sipos L, Mihály J, Karch F, Schedl P, Gausz J, Gyurkovics H
Abstract excerpt
The Abd-B gene, one of the three homeotic genes in the Drosophila bithorax complex (BX-C), is required for the proper identity of the fifth through the eighth abdominal segments (corresponding to parasegments 10-14) of the fruitfly. The morphological difference between these four segments is due...
Topics
- Abdomen
- Animals
- Central Nervous System
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Genes, Homeobox
- Genes, Insect
- Homeodomain Proteins
- Male
- Phenotype
- Point Mutation
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid
- Sequence Deletion
- Translocation, Genetic