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Article

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

The EMBO journal - 1 Aug 1990

Gyurkovics H, Gausz J, Kummer J, Karch F

Abstract excerpt

The bithorax complex specifies the identity of parasegments 5-14 of Drosophila. Although nine parasegment-specific functions, abx/bx, bxd/pbx and iab-2 to iab-8,9 have been identified, the whole bithorax complex appears to encode only three classes of proteins, Ubx, abd-A and Abd-B. Many observations suggest that the parasegment-specific functions act as positive cis-regulatory elements of Ubx, abd-A and Abd-B....

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Identifiers

PMID: 1973385
DOI: 10.1002/j.1460-2075.1990.tb07439.x
PMCID: PMC552290

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A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.PMID 1973385Read ↗

The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain.Semantic proximity Read ↗

In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element.Semantic proximity Read ↗

A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex.Semantic proximity Read ↗

Transvection in the Drosophila Abd-B domain: extensive upstream sequences are involved in anchoring distant cis-regulatory regions to the promoter.Semantic proximity Read ↗

The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex.Semantic proximity Read ↗

Cis-regulation in the Drosophila Bithorax Complex.Semantic proximity Read ↗

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The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary.Semantic proximity Read ↗

The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.Semantic proximity Read ↗

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Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex.Semantic proximity Read ↗

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