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Article

The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex.

The EMBO journal - 1 Mar 1993

Galloni M, Gyurkovics H, Schedl P, Karch F

Abstract excerpt

An extremely large cis-regulatory region generates the parasegment-specific expression patterns of the homeotic genes in the bithorax complex. We present evidence supporting the idea that this cis-regulatory region is subdivided into independent cis-regulatory domains. We describe a Ubx-lacZ transposon which is inserted into one of these domains, iab-7. The PS12-specific pattern of LacZ expression from this...

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Identifiers

PMID: 8384551
DOI: 10.1002/j.1460-2075.1993.tb05750.x
PMCID: PMC413310

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Related research

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Research trail→

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The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex.PMID 8384551Read ↗

In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element.Semantic proximity Read ↗

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.Semantic proximity Read ↗

The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain.Semantic proximity Read ↗

The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary.Semantic proximity Read ↗

Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex.Semantic proximity Read ↗

A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex.Semantic proximity Read ↗

Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex.Semantic proximity Read ↗

The Mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication.Semantic proximity Read ↗

Cis-regulation in the Drosophila Bithorax Complex.Semantic proximity Read ↗

Identification of a class of chromatin boundary elements.Semantic proximity Read ↗

The enhancer-blocking activity of the Fab-7 boundary from the Drosophila bithorax complex requires GAGA-factor-binding sites.Semantic proximity Read ↗

Transvection in the Drosophila Abd-B domain: extensive upstream sequences are involved in anchoring distant cis-regulatory regions to the promoter.Semantic proximity Read ↗

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