Article
Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.
Environmental health perspectives - 1 Jun 1997
Hong J Y, Yang C S
Abstract excerpt
Cytochrome P450 (CYP) enzymes are responsible for the metabolism of numerous xenobiotics and endogenous compounds, including the metabolic activation of most environmental toxic chemicals and carcinogens. Both metabolic and genetic polymorphisms have been identified for human CYP enzymes. The association of CYP genetic polymorphism and human cancer risk, and susceptibility to environmental hazards, have received...
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