Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.

doi:10.1289/ehp.97105s4759

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Article

Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.

Environmental health perspectives - 1 Jun 1997

Hong J Y, Yang C S

Abstract excerpt

Cytochrome P450 (CYP) enzymes are responsible for the metabolism of numerous xenobiotics and endogenous compounds, including the metabolic activation of most environmental toxic chemicals and carcinogens. Both metabolic and genetic polymorphisms have been identified for human CYP enzymes. The ass...

Topics

Biomarkers
Cytochrome P-450 Enzyme System
Genotype
Hazardous Substances
Humans
Neoplasms
Phenotype
Polymorphism, Genetic

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