Article
Two transcription activation functions in the amino terminus of the mouse estrogen receptor that are affected by the carboxy terminus.
Steroids - 1 Jul 1997
Gandini O, Kohno H, Curtis S, Korach K S
Abstract excerpt
To determine the characteristics of the N-terminal transactivation domain (AF-1) of the mouse estrogen receptor (ER), we constructed a number of deletion mutants. Wild-type and mutant receptors were expressed in yeast cells and assayed for their ability to transactivate an estrogen-responsive reporter plasmid (ERE-CYCl-LacZ) that contained a single estrogen response element of the vitellogenin A2 gene promoter....
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