Article
Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domain.
The Journal of biological chemistry - 25 Oct 1996
Chamberlain N L, Whitacre D C, Miesfeld R L
Abstract excerpt
Based on the finding that some transcription factors contain multiple transcriptional regulatory activities, we constructed a panel of rat androgen receptor (AR) mutants containing small internal deletions and point mutations within the amino-terminal region of the receptor. Trans-activation assays in CV-1 cells using AR-responsive reporter genes were performed and led to the identification of two noncontiguous...
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