Article
Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domain.
The Journal of biological chemistry - 25 Oct 1996
Chamberlain N L, Whitacre D C, Miesfeld R L
Abstract excerpt
Based on the finding that some transcription factors contain multiple transcriptional regulatory activities, we constructed a panel of rat androgen receptor (AR) mutants containing small internal deletions and point mutations within the amino-terminal region of the receptor. Trans-activation assa...
Topics
- Amino Acid Sequence
- Animals
- COS Cells
- Cell Line
- Molecular Sequence Data
- Mutagenesis
- Peptide Mapping
- Phenotype
- Protein Conformation
- Rats
- Receptors, Androgen
- Sequence Deletion
