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Article

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

The EMBO journal - 1 Mar 1992

Danielian P S, White R, Lees J A, Parker M G

Abstract excerpt

The oestrogen receptor stimulates transcription by means of at least two distinct transcriptional activation domains, TAF-1 in the N-terminal domain and TAF-2 in the hormone binding domain. Here we show that TAF-2 activity requires a region in the C-terminus of the hormone binding domain between residues 538 and 552 in the mouse oestrogen receptor which is conserved among many nuclear hormone receptors. Point...

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Identifiers

PMID: 1372244
DOI: 10.1002/j.1460-2075.1992.tb05141.x
PMCID: PMC556543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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