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Article

The N-terminal transactivation domain of rat estrogen receptor is localized in a hydrophobic domain of eighty amino acids.

Journal of biochemistry - 1 May 1991

Imakado S, Koike S, Kondo S, Sakai M, Muramatsu M

Abstract excerpt

In order to determine the transactivation domain(s) of the rat estrogen receptor (rat ER), we made a number of rat ER deletion mutants and transfected the mutant plasmids into COS7 cells together with an estrogen-responsive reporter plasmid, ERE-tk(197)-CAT, which contained the estrogen response element of Xenopus vitellogenin A2 gene. We have identified and localized the N-terminal transactivation domain of the...

Topics

Animals
Base Sequence
Chloramphenicol O-Acetyltransferase
Chromosome Deletion
DNA
Molecular Sequence Data
Mutation
Plasmids
Rats
Receptors, Estrogen
Transcriptional Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Source

Identifiers

PMID: 1917891
DOI: 10.1093/oxfordjournals.jbchem.a123441

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1917891-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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