Article
A triple mutant of the Drosophila ERR confers ligand-induced suppression of activity.
Biochemistry - 3 Jun 2003
Ostberg Tove, Jacobsson Micael, Attersand Anneli, Mata de Urquiza Alexander, Jendeberg Lena
Abstract excerpt
The steroid hormone (NR3) subfamily of nuclear receptors was until recently believed to be restricted to deuterostomes. However, a novel nuclear receptor belonging to the NR3 subfamily was recently identified in the Drosophila melanogaster genome, indicating the existence of an ancestor before the evolutionary split of deuterostomes and protostomes. This receptor, termed the Drosophila estrogen-related receptor...
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