Article
Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Apr 1997
Finger F P, Novick P
Abstract excerpt
Two new temperature-sensitive alleles of SEC3, 1 of 10 late-acting SEC genes required for targeting or fusion of post-Golgi secretory vesicles to the plasma membrane in Saccharomyces cerevisiae, were isolated in a screen for temperature-sensitive secretory mutants that are synthetically lethal with sec4-8. The new sec3 alleles affect early as well as late stages of secretion. Cloning and sequencing of the SEC3...
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