Article
Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton.
Traffic (Copenhagen, Denmark) - 1 Nov 2012
Jourdain Isabelle, Dooley Hannah C, Toda Takashi
Abstract excerpt
The exocyst complex tethers post-Golgi secretory vesicles to the plasma membrane prior to docking and fusion. In this study, we identify Sec3, the missing component of the Schizosaccharomyces pombe exocyst complex (SpSec3). SpSec3 shares many properties with its orthologs, and its mutants are rescued by human Sec3/EXOC1. Although involved in exocytosis, SpSec3 does not appear to mark the site of exocyst complex...
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