Article
Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum.
Molecular biology of the cell - 1 Dec 2003
Wiederkehr Andreas, Du Yunrui, Pypaert Marc, Ferro-Novick Susan, Novick Peter
Abstract excerpt
Sec3p is a component of the exocyst complex that tethers secretory vesicles to the plasma membrane at exocytic sites in preparation for fusion. Unlike all other exocyst structural genes, SEC3 is not essential for growth. Cells lacking Sec3p grow and secrete surprisingly well at 25 degrees C; howe...
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