Article
Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain.
The Journal of cell biology - 1 Jun 1990
Nair J, Müller H, Peterson M, Novick P
Abstract excerpt
SEC2 function is required at the post-Golgi apparatus stage of the yeast secretory pathway. The SEC2 sequence encodes a protein product of 759 amino acids containing an amino terminal region that is predicted to be in an alpha-helical, coiled-coil conformation. Two temperature-sensitive alleles, sec2-41 and sec2-59, encode proteins truncated by opal stop codons and are suppressible by an opal tRNA suppressor....
Topics
- Amino Acid Sequence
- Amino Acids
- Animals
- Base Sequence
- Biological Transport
- Chromosome Mapping
- Cloning, Molecular
- GTP-Binding Proteins
- Guanine Nucleotide Exchange Factors
- Molecular Sequence Data
- Mutation