Article
Induction of multiple PCR-SSCPE mobility shifts in p53 exons in cultures of normal human urothelium exposed to low-dose gamma-radiation.
International journal of radiation biology - 1 Jul 1997
Colucci S, Mothersill C, Harney J, Gamble S C, Seymour C, Arrand J E
Abstract excerpt
We have previously shown that primary explant cultures of human urothelium exposed to low doses of gamma-radiation subsequently accumulate a high level of stable p53 but it was not clear from those studies whether this protein stabilization occurred through an event in another gene involved in p53 protein control or possibly an epigenetic event. In these experiments, primary urothelial cultures from five...
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