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Article

A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation

1 Mar 2003

Abstract excerpt

The aim of this study was to test whether radiation-induced bystander effects are involved in the response of multicellular systems to targeted irradiation. A primary explant technique was used that reconstructed the in vivo microarchitecture of normal urothelium with proliferating and differentiated cells present. Sections of human and porcine ureter were cultured as explants and irradiated on day 7 when the...

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PMID: 12618888
DOI: 10.1038/sj.bjc.6600804

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