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Article

A new thiamin salvage pathway.

Nature chemical biology - 1 Aug 2007

Jenkins Amy Haas, Schyns Ghislain, Potot Sébastien, Sun Guangxing, Begley Tadhg P

Abstract excerpt

The physiological function for thiaminase II, a thiamin-degrading enzyme, has eluded investigators for more than 50 years. Here, we demonstrate that this enzyme is involved in the regeneration of the thiamin pyrimidine rather than in thiamin degradation, and we identify a new pathway involved in the salvage of base-degraded forms of thiamin. This pathway is widely distributed among bacteria, archaea and...

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PMID: 17618314
DOI: 10.1038/nchembio.2007.13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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