Article
Identification of the thiamin salvage enzyme thiazole kinase in Arabidopsis and maize.
Phytochemistry - 1 Oct 2013
Yazdani Mohammad, Zallot Rémi, Tunc-Ozdemir Meral, de Crécy-Lagard Valérie, Shintani David K, Hanson Andrew D
Abstract excerpt
The breakdown of thiamin (vitamin B1) and its phosphates releases a thiazole moiety, 4-methyl-5-(2-hydroxyethyl)thiazole (THZ), that microorganisms and plants are able to salvage for re-use in thiamin synthesis. The salvage process starts with the ATP-dependent phosphorylation of THZ, which in bacteria is mediated by ThiM. The Arabidopsis and maize genomes encode homologs of ThiM (At3g24030 and GRMZM2G094558,...
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