Mouse zeta- and alpha-globin genes: embryonic survival, alpha-thalassemia, and genetic background effects.

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Article

Mouse zeta- and alpha-globin genes: embryonic survival, alpha-thalassemia, and genetic background effects.

Blood - 1 Aug 1997

Leder A, Daugherty C, Whitney B, Leder P

Abstract excerpt

A classical notion regarding the expression of murine embryonic zeta- and adult alpha-globin genes holds that there is a switch in globin production from the embryonic to the adult form during fetal development. Our previous in situ hybridization studies challenged this view, since both zeta- and...

Topics

Alleles
Animals
Embryonic and Fetal Development
Epistasis, Genetic
Erythropoiesis
Fetal Blood
Fetal Death
Gene Expression Regulation, Developmental
Gene Targeting
Genotype
Globins
Mice
Mice, Inbred BALB C
Mice, Inbred Strains
Mice, Knockout
Recombination, Genetic
Stem Cells
alpha-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 9242562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9242562-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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